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Clinical Trials

Clinical research plays a vital role in the war on cancer.  Through research we discover new and better ways to fight this disease, improve the quality of life for patients, and ultimately one day, to prevent cancer.  Research studies, also called clinical trials or protocols, help develop better treatments to improve survival, understand how cancer grows and manage side effects of treatment to improve quality of life. 
Pearlman offers clinical trials sponsored by the National Cancer Institute as well as pharmaceutical companies.

Clinical Trials: Protocols Available by Disease Site



SWOG 1007
A Phase III, Randomized Clinical Trial of Standard Adjuvant Endocrine Therapy +/- Chemotherapy in Patients with 1-3 Positive Nodes, Hormone Receptor-Positive and HER-2 Negative Breast Cancer with Recurrence Score (RS) of 25 or Less.

SWOG 1202
A Randomized Placebo-Controlled Phase III Study of Duloxetine for Treatment of Aromatase Inhibitor-Associated Musculoskeletal Symptoms in Women with Early Stage Breast Cancer

SWOG 1207
Phase III Randomized, Placebo-Controlled Clinical Trial Evaluating the Use of Adjuvant Endocrine Therapy +/- One Year of Everolimus in Patients with High-Risk, Hormone Receptor-Positive and HER2/neu Negative Breast Cancer


SWOG 1222
Fulvestrant Alone Versus Fulvestrant and Everolimus Versus Fulvestrant, Everolimus and Anastrozole: A Phase III Randomized Placebo-Controlled Trial in Postmenopausal Patients



A Phase III Trial of 6 versus 12 Treatments of Adjuvant FOLFOX plus Celecoxib or Placebo for Patients with Resected Stage III Colon Cancer


SWOG 0931
EVEREST:  EVErolimus for Renal Cancer Ensuing Surgical Therapy, A Phase III Study

Non-Small Cell Lung Cancer

Randomized Phase III Study of Maintenance Therapy with Bevacizumab, Pemetrexed, or a Combination of Bevacizumab and Pemetrexed Following Carboplatin, Paclitaxel and Bevacizumab for Advanced Non-Squamous NSCLC

SWOG 1400
Phase II/III Biomarker-Driven Master Protocol for Second Line Therapy of Squamous Cell Lung Cancer


CTSU E1609
A Phase III Randomized Study of Adjuvant Ipilimumab Anti-CTLA4 Therapy Versus High-Dose Interferon α-2b for Resected High-Risk Melanoma

The following disease sites have no studies available at this time: Gallbladder, Genitourinary, GIST, Head and Neck, Leukemia, Lymphoma, Myeloma, Pancreas and Prostate.